Publications

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Osteoarthritis and Cartilage
2025

Aging-associated Increase of GATA4 levels in Articular Cartilage is Linked to Impaired Regenerative Capacity of Chondrocytes and Osteoarthritis

Meagan Makarczyk, Yiqian Zhang, Alyssa Aguglia, Olivia Bartholomew, Sophie Hines, Suyash Sinkar, Silvia Liu, Craig Duvall, and Hang Lin
Biomaterials Science
2025

From saccharides to synthetics: exploring biomaterial scaffolds as cell transduction enhancers

Micah Mallory, Emma Grace Johnson, Soumen Saha, Sanika Pandit, Joshua T. McCune, Mengnan Dennis, Jessica M. Gluck, Craig L. Duvall, Ashley C. Brown, Ashutosh Chilkoti, and Yevgeny Brudno
ACS Biomaterials Science & Engineering
2025

Cooling-Triggered Release of Celecoxib from Implantable Alginate-Soluplus Composite Devices

Romario Lobban, Michael Carroll, Victoria Vest, Josh T. McCune, Sarah Hall, Fang Yu, Md. Jashim Uddin, Lawrence J. Marnett, Craig L. Duvall, and Leon M. Bellan
Molecular Pharmaceutics
2025

Polymeric Nanoparticles Enable Targeted Visualization of Drug Delivery in Breast Cancer

Md. Jashim Uddin, Justin H. Lo, Mukesh K. Gupta, Thomas A. Werfel, Abu Asaduzzaman, Connor G. Oltman, Eva F. Gbur, Mohammed T. Mohyuddin, Farhana Nazmin, Md. Saidur Rahman, Ahan Jashim, Brenda C. Crews, Philip J. Kingsley, Jamie E. Klendworth, Lawrence J. Marnett, Craig L. Duvall, and Rebecca S. Cook
Cancer Research Communication
2025

Induction of Triple-Negative Breast Cancer Cell Death and Chemosensitivity Using mTORC2-Directed RNAi Nanomedicine

Shrusti S. Patel, Rebecca S. Cook, Justin H. Lo, Fiona K. Cherry, Ella N. Hoogenboezem, Fang Yu, Nora Francini, Nina T. Cassidy, Joshua T. McCune, Eva F. Gbur, Lisa Messier, Thomas A. Dean, Kalin L. Wilson, Dana M. Brantley-Sieders, and Craig L. Duvall
Nature BME
2025

siRNA conjugate with high albumin affinity and degradation resistance for delivery and treatment of arthritis in mice and guinea pigs

Juan M. Colazo, Megan C. Keech, Veeraj Shah, Ella N. Hoogenboezem, Justin H. Lo, Nora Francini, Nina T. Cassidy, Fang Yu, Alexander G. Sorets, Joshua T. McCune, Carlisle R. DeJulius, Hongsik Cho, Danielle L. Michell, Tristan Maerz, Kacey C. Vickers, Katherine N. Gibson-Corley, Karen A. Hasty, Leslie J. Crofford, Rebecca S. Cook & Craig L. Duvall
Osteoarthritis Cartilage
2025

A programmable arthritis-specific receptor for guided articular cartilage regenerative medicine

Bonnie L Walton, Rebecca Shattuck-Brandt, Catherine A Hamann, Victoria W Tung, Juan M Colazo, David D Brand, Karen A Hasty, Craig L Duvall, Jonathan M Brunger
Biomaterials
2025

Intravascular delivery of an MK2 inhibitory peptide to prevent restenosis after angioplasty

J William Tierney, R Paolo Francisco, Fang Yu, Jinqi Ma, Joyce Cheung-Flynn, Megan C Keech, Richard D'Arcy, Veeraj M Shah, Anna R Kittel, Devin J Chang, Joshua T McCune, Mariah G Bezold, Adrian N Aligwekwe, Rebecca S Cook, Joshua A Beckman, Colleen M Brophy, Craig L Duvall
Biomaterials
2025

Shear-thinning hydrogel for allograft cell transplantation and externally controlled transgene expression

Mariah G Bezold, Bryan R Dollinger, Carlisle R DeJulius, Megan C Keech, Andrew R Hanna, Anna R Kittel, Fang Yu, Mukesh K Gupta, Richard D'Arcy, Jonathan M Brunger, Craig L Duvall
Journal of Orthopaedic Research
2024

Teaming up to overcome challenges toward translation of new therapeutics for osteoarthritis

Carla R Scanzello, Karen A Hasty, Christine B Chung, Timothy M Griffin, Nick J Willet, Hollis Krug, Cong-Qiu Chu, David Ewart, Saeed Jerban, Joshua F Baker, Craig L Duvall, Jonathan M Brunger, Jason A Burdick, Kurt P Spindler, Hicham Drissi
Journal of Molecular Biology
2024

A Nanobody Toolbox for Recognizing Distinct Epitopes on Cas9

Jack Boylan, Rebecca A Shrem, Isabel Vallecillo-Viejo, Craig L Duvall, Brian E Wadzinski, Benjamin W Spiller
Nature Communications
2024

Structural optimization of siRNA conjugates for albumin binding achieves effective MCL1-directed cancer therapy

Ella N. Hoogenboezem, Shrusti S. Patel, Justin H. Lo, Ashley B. Cavnar, Lauren M. Babb, Nora Francini, Eva F. Gbur, Prarthana Patil, Juan M. Colazo, Danielle L. Michell, Violeta M. Sanchez, Joshua T. McCune, Jinqi Ma, Carlisle R. DeJulius, Linus H. Lee, Jonah C. Rosch, Ryan M. Allen, Larry D. Stokes, Jordan L. Hill, Kasey C. Vickers, Rebecca S. Cook & Craig L. Duvall
Nature Reviews Rheumatology
2024

Engineering approaches for RNA-based and cell-based osteoarthritis therapies

Carlisle R. DeJulius, Bonnie L. Walton, Juan M. Colazo, Richard d’Arcy, Nora Francini, Jonathan M. Brunger & Craig L. Duvall
ACS Nano
2023

Nonviral In Vivo Delivery of CRISPR-Cas9 Using Protein-Agnostic, High-Loading Porous Silicon and Polymer Nanoparticles

R. Brock Fletcher, Larry D. Stokes, Isom B. Kelly III, Katelyn M. Henderson, Isabel C. Vallecillo-Viejo, Juan M. Colazo, Benjamin V. Wong, Fang Yu, Richard d’Arcy, Morgan N. Struthers, Brian C. Evans, Jacob Ayers, Matthew Castanon, Michael J. Weirich, Sarah K. Reilly, Shrusti S. Patel, Yoanna I. Ivanova, Carlos A. Silvera Batista, Sharon M. Weiss, Charles A. Gersbach, Jonathan M. Brunger, and Craig L. Duvall
Cells
2023

Newly Developed Di-Block Copolymer-Based Cell Membrane Stabilizers Protect Mouse Coronary Artery Endothelial Cells against Hypoxia/Reoxygenation Injury

Zhu Li, Mukesh K. Gupta, Matthew B. Barajas, Takuro Oyama, Craig L. Duvall, and Matthias L. Riess
Advanced Functional Materials
2023

Hybrid Shear-Thinning Hydrogel Integrating Hyaluronic Acid with ROS-Responsive Nanoparticles

Mariah G. Bezold, Andrew R. Hanna, Bryan R. Dollinger, Prarthana Patil, Fang Yu, Craig L. Duvall, Mukesh K. Gupta
Nature Biomedical Engineering
2023

Suppression of local inflammation via galectin-anchored indoleamine 2,3-dioxygenase

Evelyn Bracho-Sanchez, Fernanda G. Rocha, Sean K. Bedingfield, Brittany D. Partain, Sabrina L. Macias, Maigan A. Brusko, Juan M. Colazo, Margaret M. Fettis, Shaheen A. Farhadi, Eric Y. Helm, Kevin Koenders, Alexander J. Kwiatkowski, Antonietta Restuccia, Bethsymarie Soto Morales, Arun Wanchoo, Dorina Avram, Kyle D. Allen, Craig L. Duvall, Shannon M. Wallet, Gregory A. Hudalla & Benjamin G. Keselowsky
Biomaterials
2023

Core polymer optimization of ternary siRNA nanoparticles enhances in vivo safety, pharmacokinetics, and tumor gene silencing

Shrusti S. Patel, Ella N. Hoogenboezem, Fang Yu, Carlisle R. DeJulius, Brock Fletcher, Alex G. Sorets, Fiona K. Cherry, Justin H. Lo, Mariah G. Bezold, Nora Francini, Richard d’Arcy, Jordan E. Brasuell, Rebecca S. Cook, Craig L. Duvall
Antioxidants
2023

Intraocular Sustained Release of EPO-R76E Mitigates Glaucoma Pathogenesis by Activating the NRF2/ARE Pathway

Sarah Naguib, Carlisle R. DeJulius, Jon R. Backstrom, Ameer A. Haider, John M. Ang, Andrew M. Boal, David J. Calkins, Craig L. Duvall and Tonia S. Rex
Cellular and Molecular Bioengineering
2022

Albumin-Binding Aptamer Chimeras for Improved siRNA Bioavailability

JC Rosch, EN Hoogenboezem, AG Sorets, CL Duvall*, ES Lippmann*
Biophysical Journal
2022

Visualizing the lipid dynamics role in infrared neural stimulation using stimulated Raman scattering

WR Adams, R Gautam, A Locke, Masson LE, AI Borrachero-Conejo, B Dollinger†, GA Throckmorton, CL Duvall, ED Jansen, A Mahadevan-Jansen
Science Translational Medicine
2022

ROS-Degradable Polythioketal Urethane Foam Dressings to Promote Porcine Skin Wound Repair

P Patil, KA Russo, JT McCune, AC Pollins, MA Cottam, BR Dollinger, CR DeJulius, MK Gupta, R D’Arcy, JM Colazo, F Yu, MG Bezold, JR Martin, NL Cardwell, JM Davidson, CM Thompson, A Barbul, AM Hasty, SA Guelcher, CL Duvall
ACS Chemical Biology
2022

Discovery of a Redox-Activatable Chemical Probe for Detection of Cyclooxygenase-2 in Cells and Animals

MJ Uddin, JH Lo, CG Oltman, BC Crews, T Huda, J Liu, PJ Kingsley, S Lin, M Milad, AM Aleem, A Asaduzzaman, JO McIntyre, CL Duvall, LJ Marnett
Molecular Reproduction and Development
2022

Nanoparticle-mediated transgene expression of insulin-like growth factor 1 in the growth restricted guinea pig placenta increases placenta nutrient transporter expression and fetal glucose concentrations

RL Wilson, K Lampe, MK Gupta, CL Duvall, HN Jones
Journal of the American Chemical Society
2022

A Reactive Oxygen Species-Scavenging ‘Stealth’ Polymer, Poly(thioglycidyl glycerol), Outperforms Poly(ethylene glycol) in Protein Conjugates and Nanocarriers and Enhances Protein Stability to Environmental and Biological Stressors

R d’Arcy, F El Mohtadi, N Francini, CR DeJulius, H Back, A Gennari, M Geven, M Lopez-Cavestany, ZY Turhan, F Yu, JB Lee, MR King, L Kagan, CL Duvall, N Tirelli