Advanced Healthcare Materials
2020
Amphiphilic Polyelectrolyte Graft Copolymers Enhance the Activity of Cyclic Dinucleotide STING Agonists
Nguyen DC, Shae D, Pagendarm HM, Becker KW, Wehbe M, Kilchrist KV, Pastora LE, Palmer CR, Seber P, Christov PP, Duvall CL, Wilson JT
Biomaterials
2020
Kupffer Cell Release of Platelet Activating Factor Drives Dose Limiting Toxicities of Nucleic Acid Nanocarriers
Jackson MA, Patel SS, Yu Fang, Cottam MA, Glass EB, Hoogenboezem EN, Fletcher RB, Dollinger BR, Patil P, Liu Danielle, Kelly IB, Bedingfield SK, King AR, Miles RE, Hasty AM, Giorgio TD, Duvall CL
Journal of Orthopaedic Research
2020
Diflunisal - loaded poly(propylene sulfide) nanoparticles decrease S. aureus - mediated bone destruction during osteomyelitis
Ford CA, Spoonmore TJ, Gupta MK, Duvall CL, Guelcher SA, Cassat JE
Tissue Engineering A
2019
Nanotechnology enabled modulation of signaling pathways affects physiologic responses in intact vascular tissue
KM Hocking, BC Evans, P Komalavilas, J Cheung-Flynn CL Duvall, and CM Brophy
Tissue Engineering A
2019
Poly(thioketal urethane) Autograft Extenders in an Intertransverse Process Model of Bone Formation
MAP McGough, SM Shiels, LA Boller, KJ Zienkiewicz, CL Duvall, JC Wenke, SA Guelcher
Biomaterials
2019
Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes
MA Jackson, SK Bedingfield, F Yu, ME Stokan, RE Miles, EJ Curvino, EN Hoogenboezem, RH Bonami, SS Patel, PL Kendall, TD Giorgio, CL Duvall
ACS Nano
2019
Gal8 Visualization of Endosome Disruption Predicts Carrier-mediated Biologic Drug Intracellular Bioavailability
KV Kilchrist, SC Dimobi, MA Jackson, BC Evans, TA Werfel, EA Dailing, SK Bedingfield, IB Kelly, CL Duvall
AJP-Endocrinology and Metabolism
2019
Rapid changes in the microvascular circulation of skeletal muscle impair insulin delivery during sepsis
N Mignemi, P McClatchey, KV Kilchrist, I Williams, B Millis, K Syring, CL Duvall, D Wasserman, O McGuinness
Cellular and Molecular Bioengineering
2019
PLGA Microparticle Depots for Controlled and Sustained Release of Endosomolytic Nanoparticles
K Garland, S Sevimli, KV Kilchrist, CL Duvall, RS Cook, JT Wilson
European Journal of Pharmaceutical Science
2019
Preparation, preliminary pharmacokinetic and brain targeting study of metformin encapsulated W/O/W composite submicron emulsions promoted by borneol
L Hong, X Li, Y Bao, CL Duvall, C Zhang, W Chen, C Peng
Tissue Engineering B
2019
Applied Bioengineering in Tissue Reconstruction, Replacement, and Regeneration
JM Colazo, BC Evans, AF Farinas, S Al-Kassis, CL Duvall. WP Thayer
ACS Omega
2019
Optimizing Conjugation Efficiency and Residual Copper-Associated Toxicity in CuAAC-Functionalized Polyplexes for Delivery to Tumor-Associated Macrophages
EB Glass, S Masjedi, SO Dudzinski, AJ Wilson, CL Duvall, FE Yull, TD Giorgio
Journal of Controlled Release
2019
Systemic Delivery of a Gli Inhibitor via Polymeric Nanocarriers Blocks Tumor-Induced Bone Disease
JP Vanderburgh, KA Kwakwa, TA Werfel, AR Merkel, MK Gupta, RW Johnson, SA Guelcher, CL Duvall, JA Rhoades Sterling
Nature Communications
2019
Optimization of an Anionic, Endosome-Escaping Polymer to Potentiate Intracellular Delivery of Cationic Peptides, Biomacromolecules, and Nanoparticles
BC Evans, RB Fletcher, KV Kilchrist, EA Dailing, AJ Mukalel, JM Colazo, M Oliver, J Cheung-Flynn, CM Brophy, JW Tierney, JS Isenberg, KD Hankenson, K Ghimire, C Lander, CA Gersbach, CL Duvall
ACS Biomaterials Science & Engineering
2018
Drug Free ROS Sponge Polymeric Microspheres Reduce Tissue Damage from Ischemic and Mechanical Injury
KP O’Grady, TE Kavanaugh, H Cho, H Ye, MK Gupta, MC Madonna, J Lee, CM O’Brien, MC Skala, KA Hasty, CL Duvall
Cell Death and Disease
2018
Intrinsic Apoptotic Pathway Activation Increases Response to Anti-Estrogens in Luminal Breast Cancers
MM Williams, L Lee, TA Werfel, MM Joly, DJ Hicks, B Rahman, D Elion, C McKernan, V Sanchez, V Estrada, S Massarweh, R Elledge, CL Duvall, RS Cook
Journal of Biomedical Materials Research A
2018
Formulation and characterization of poly(propylacrylic acid)/poly(lactic-co-glycolic acid) blend microparticles for pH-dependent membrane disruption and cytosolic delivery
LP Fernando, JS Lewis, BC Evans, CL Duvall, BG Keselowsky
Cancer Research
2018
Selective mTORC2 inhibitor therapeutically blocks breast cancer cell growth and survival
TA Werfel, S Wang, MA Jackson, TE Kavanaugh, MM Joly, L Lee, DJ Hicks, VM Sanchez, PI Gonzalez-Ericsson, KV Kilchrist, SC Dimobi, SM Sarett, DM Brantley-Sieders , RS Cook, CL Duvall
Journal of Controlled Release
2018
Excipients for the Lyoprotection of MAPKAP Kinase 2 Inhibitory Peptide Nano-Polyplexes
AJ Mukalel, BC Evans, KV Kilchrist, EA Dailing, B Burdette, J Cheung-Flynn, CM Brophy, CL Duvall
Advanced Drug Delivery Reviews
2018
Harnessing Albumin as a Carrier for Cancer Therapies
EN Hoogenboezem, CL Duvall
Perfusion
2017
Unregulated saphenous vein graft distension decreases tissue viscoelasticity
ES Wise, KM Hocking, BC Evans, CL Duvall, J Cheung-Flynn, CM Brophy
Journal of Controlled Release
2017
Combinatorial Optimization of PEG Architecture and Hydrophobic Content Improves siRNA Polyplex Stability, Pharmacokinetics, and Potency In Vivo
TA Werfel, MA Jackson, TE Kavanaugh, KC Kirkbride, M Miteva, TD Giorgio, CL Duvall
ACS Nano
2017
Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol
MA Jackson, TA Werfel, E Curvino, F Yu, TE Kavanaugh, SM Sarett, M Dockery, KV Kilchrist, A Jackson, TD Giorgio, CL Duvall
Bioengineering & Translational Medicine
2017
Poly(2-propylacrylic acid) / poly(lactic-co-glycolic acid) blend microparticles as a targeted antigen delivery system to direct either CD4+ or CD8+ T cell activation
L Yang, E Bracho-Sanchez, MR Carstens, LP Fernando, JS Lewis, CL Duvall, BG Keselowsky
PNAS
2017
Lipophilic siRNA Targets Albumin in Situ and Promotes Bioavailability, Tumor Penetration, and Carrier-Free Gene Silencing
SM Sarett, TA Werfel, L Lee, MA Jackson, KV Kilchrist, DM Brantley-Sieders, CL Duvall
