Bioconjugate Chemistry
2021
Optimizing an Antioxidant TEMPO Copolymer for Reactive Oxygen Species Scavenging and Anti-Inflammatory Effects in Vivo
CR DeJulius, BR Dollinger, TE Kavanaugh, E Dailing, F Yu, S Gulati, A Miskalis, C Zhang, J Uddin, S Dikalov, CL Duvall
Acta Biomaterials
2021
Effects of nanocrystalline hydroxyapatite concentration and skeletal site on bone and cartilage formation in rats
LA Boller, SM Shiels, DC Florian, SH Peck, JG Schoenecker, CL Duvall, JC Wenke, SA Guelcher
Materials
2021
Settable Polymeric Autograft Extenders in a Rabbit Radius Model of Bone Formation
LA Boller, MA McGough, SM Shiels, CL Duvall, JC Wenke, SA Guelcher
ACS Applied Materials and Interfaces
2021
Shape-Defined microPlates for the Sustained Intra-articular Release of Dexamethasone in the Management of Overload-Induced Osteoarthritis
M Di Francesco, SK Bedingfield, V Di Francesco, JM Colazo, F Yu, L Ceseracciu, E Bellotti, D Di Mascolo, M Ferreira, LE Himmel, CL Duvall*, P Decuzzi*
ACS Nano
2021
Top-Down Fabricated microPlates for Prolonged, Intra-articular Matrix Metalloproteinase 13 siRNA Nanocarrier Delivery to Reduce Post-traumatic Osteoarthritis
SK Bedingfield, JM Colazo, M Di Francesco, F Yu, DD Liu, V Di Francesco, LE Himmel, MK Gupta, H Cho, KA Hasty, P Decuzzi, CL Duvall
Nature Biomedical Engineering
2021
Amelioration of post-traumatic osteoarthritis via nanoparticle depots delivering small interfering RNA to damaged cartilage
SK Bedingfield, JM Colazo, F Yu, DD Liu, MA Jackson, LE Himmel, H Cho, LJ Crofford, KA Hasty, CL Duvall
JCI Insight
2021
Therapeutic MK2 Inhibition Blocks Pathological Vascular Smooth Muscle Cell Phenotype Switch
JW Tierney, BC Evans, J Cheung-Flynn, B Wang, JM Colazo, ME Polcz, RS Cook, CM Brophy, CL Duvall.
ACS Biomaterials Science & Engineering
2020
Nanocrystalline hydroxyapatite-poly(thioketal urethane) nanocomposites stimulate a combined intramembranous and endochondral ossification response in rabbits
M McGough, L Boller, D Groff, J Schoenecker, J Nyman, JC Wenke, C Rhodes, D Shimko, CL Duvall, SA Guelcher
ACS Applied Materials and Interfaces
2020
Endosomolytic mesoporous silica nanoparticles for siRNA/miRNA combination therapy of metastatic cancer
Y Wang, Y Xie, J Li, KV Kilchrist, CL Duvall, D Oupický
ACS Nano
2020
Tuning Ligand Density to Optimize Pharmacokinetics of Targeted Nanoparticles for Dual Protection against Tumor-Induced Bone Destruction
JP Vanderburgh, JL Hill, MK Gupta, KA Kwakwa, SK Wang, KE Moyer, SK Bedingfield, AR Merkel, R d’Arcy SA Guelcher, JA Rhoades, CL Duvall
ACS Medicinal Chemistry Letters
2020
Molecular Imaging of Inflammation in Osteoarthritis Using a Water-soluble Fluorocoxib
MJ Uddin, A Vemulapalli, H Niitsu, BC Crews, CG Oltman, PJ Kingsley, TE Kavanaugh, SK Bedingfield, JO McIntyre, M Milad, AM Aleem, RJ Coffey, CL Duvall, LJ Marnett
Pharmaceutical Research
2020
DNA Polyplexes of a Phosphorylcholine-Based Zwitterionic Polymer for Gene Delivery
KM Dave, L Han, MA Jackson, L Kadlecik, CL Duvall, DS Manickam
ACS Sensors
2020
Genetically Encoded Split-Luciferase Biosensors to Measure Endosome Disruption Rapidly in Live Cells
KV Kilchrist, JW Tierney, CL Duvall
ACS Applied Materials and Interfaces
2020
Tuning Composition of Polymer and Porous Silicon Composite Nanoparticles for Early Endosome Escape of Anti-microRNA Peptide Nucleic Acids
IB Kelly, RB Fletcher, JR McBride, SM Weiss, CL Duvall
ACS Chemical Biology
2020
Visualizing HIF-1α mRNA in a Subpopulation of Bone Marrow-Derived Cells to Predict Retinal Neovascularization
MI Uddin, TC Kilburn, CL Duvall, JS Penn
ACS Central Science
2020
Structural Optimization of Polymeric Carriers to Enhance the Immunostimulatory Activity of Molecularly Defined RIG-I Agonists
ME Jacobson, KW Becker, CR Palmer, LE Pastora, RB Fletcher, KA Collins, O Fedorova, CL Duvall, AM Pyle, JT Wilson
ACS Applied Materials and Interfaces
2020
Modifying cell membranes with anionic polymer amphiphiles potentiates intracellular delivery of cationic peptides
EA Dailing, KV Kilchrist, JW Tierney, RB Fletcher, BC Evans, CL Duvall
Biomaterials
2020
Enhanced stem cell retention and antioxidative protection with injectable, ROS-degradable PEG hydrogels
JR Martin, P Patil, F Yu, MK Gupta, CL Duvall
Current Opinion in Chemical Engineering
2020
Caveolae-mediated transport at the injured blood–brain barrier as an underexplored pathway for central nervous system drug delivery
AG Sorets, JC Rosch, CL Duvall, ES Lippmann
Advanced Healthcare Materials
2020
Amphiphilic Polyelectrolyte Graft Copolymers Enhance the Activity of Cyclic Dinucleotide STING Agonists
Nguyen DC, Shae D, Pagendarm HM, Becker KW, Wehbe M, Kilchrist KV, Pastora LE, Palmer CR, Seber P, Christov PP, Duvall CL, Wilson JT
Biomaterials
2020
Kupffer Cell Release of Platelet Activating Factor Drives Dose Limiting Toxicities of Nucleic Acid Nanocarriers
Jackson MA, Patel SS, Yu Fang, Cottam MA, Glass EB, Hoogenboezem EN, Fletcher RB, Dollinger BR, Patil P, Liu Danielle, Kelly IB, Bedingfield SK, King AR, Miles RE, Hasty AM, Giorgio TD, Duvall CL
Journal of Orthopaedic Research
2020
Diflunisal - loaded poly(propylene sulfide) nanoparticles decrease S. aureus - mediated bone destruction during osteomyelitis
Ford CA, Spoonmore TJ, Gupta MK, Duvall CL, Guelcher SA, Cassat JE
Tissue Engineering A
2019
Nanotechnology enabled modulation of signaling pathways affects physiologic responses in intact vascular tissue
KM Hocking, BC Evans, P Komalavilas, J Cheung-Flynn CL Duvall, and CM Brophy
Tissue Engineering A
2019
Poly(thioketal urethane) Autograft Extenders in an Intertransverse Process Model of Bone Formation
MAP McGough, SM Shiels, LA Boller, KJ Zienkiewicz, CL Duvall, JC Wenke, SA Guelcher
Biomaterials
2019
Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes
MA Jackson, SK Bedingfield, F Yu, ME Stokan, RE Miles, EJ Curvino, EN Hoogenboezem, RH Bonami, SS Patel, PL Kendall, TD Giorgio, CL Duvall
