Biomaterials
2019
Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes
MA Jackson, SK Bedingfield, F Yu, ME Stokan, RE Miles, EJ Curvino, EN Hoogenboezem, RH Bonami, SS Patel, PL Kendall, TD Giorgio, CL Duvall
Tissue Engineering A
2019
Poly(thioketal urethane) Autograft Extenders in an Intertransverse Process Model of Bone Formation
MAP McGough, SM Shiels, LA Boller, KJ Zienkiewicz, CL Duvall, JC Wenke, SA Guelcher
Tissue Engineering A
2019
Nanotechnology enabled modulation of signaling pathways affects physiologic responses in intact vascular tissue
KM Hocking, BC Evans, P Komalavilas, J Cheung-Flynn CL Duvall, and CM Brophy
Advanced Drug Delivery Reviews
2018
Harnessing Albumin as a Carrier for Cancer Therapies
EN Hoogenboezem, CL Duvall
Journal of Controlled Release
2018
Excipients for the Lyoprotection of MAPKAP Kinase 2 Inhibitory Peptide Nano-Polyplexes
AJ Mukalel, BC Evans, KV Kilchrist, EA Dailing, B Burdette, J Cheung-Flynn, CM Brophy, CL Duvall
Cancer Research
2018
Selective mTORC2 inhibitor therapeutically blocks breast cancer cell growth and survival
TA Werfel, S Wang, MA Jackson, TE Kavanaugh, MM Joly, L Lee, DJ Hicks, VM Sanchez, PI Gonzalez-Ericsson, KV Kilchrist, SC Dimobi, SM Sarett, DM Brantley-Sieders , RS Cook, CL Duvall
Journal of Biomedical Materials Research A
2018
Formulation and characterization of poly(propylacrylic acid)/poly(lactic-co-glycolic acid) blend microparticles for pH-dependent membrane disruption and cytosolic delivery
LP Fernando, JS Lewis, BC Evans, CL Duvall, BG Keselowsky
Cell Death and Disease
2018
Intrinsic Apoptotic Pathway Activation Increases Response to Anti-Estrogens in Luminal Breast Cancers
MM Williams, L Lee, TA Werfel, MM Joly, DJ Hicks, B Rahman, D Elion, C McKernan, V Sanchez, V Estrada, S Massarweh, R Elledge, CL Duvall, RS Cook
ACS Biomaterials Science & Engineering
2018
Drug Free ROS Sponge Polymeric Microspheres Reduce Tissue Damage from Ischemic and Mechanical Injury
KP O’Grady, TE Kavanaugh, H Cho, H Ye, MK Gupta, MC Madonna, J Lee, CM O’Brien, MC Skala, KA Hasty, CL Duvall
Advanced Functional Materials
2017
Thermogelling, ABC Triblock Copolymer Platform for Resorbable Hydrogels with Tunable, Degradation-Mediated Drug Release
MK Gupta, JR Martin, BR Dollinger, ME Hattaway, CL Duvall
Tissue Engineering Part C: Methods
2017
Porcine Ischemic Wound Healing Model for Preclinical Testing of Degradable Biomaterials
P Patil, JR Martin, SM Sarett, AC Pollins, NL Cardwell, JM Davidson, SA Guelcher, LB Nanney, CL Duvall
Tissue Engineering A
2017
ROS-shielding hydrogel for the delivery of adherent and non-adherent therapeutic cell types
BR Dollinger, MK Gupta, JR Martin, CL Duvall
PNAS
2017
Lipophilic siRNA Targets Albumin in Situ and Promotes Bioavailability, Tumor Penetration, and Carrier-Free Gene Silencing
SM Sarett, TA Werfel, L Lee, MA Jackson, KV Kilchrist, DM Brantley-Sieders, CL Duvall
Bioengineering & Translational Medicine
2017
Poly(2-propylacrylic acid) / poly(lactic-co-glycolic acid) blend microparticles as a targeted antigen delivery system to direct either CD4+ or CD8+ T cell activation
L Yang, E Bracho-Sanchez, MR Carstens, LP Fernando, JS Lewis, CL Duvall, BG Keselowsky
ACS Nano
2017
Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol
MA Jackson, TA Werfel, E Curvino, F Yu, TE Kavanaugh, SM Sarett, M Dockery, KV Kilchrist, A Jackson, TD Giorgio, CL Duvall
Journal of Controlled Release
2017
Combinatorial Optimization of PEG Architecture and Hydrophobic Content Improves siRNA Polyplex Stability, Pharmacokinetics, and Potency In Vivo
TA Werfel, MA Jackson, TE Kavanaugh, KC Kirkbride, M Miteva, TD Giorgio, CL Duvall
Perfusion
2017
Unregulated saphenous vein graft distension decreases tissue viscoelasticity
ES Wise, KM Hocking, BC Evans, CL Duvall, J Cheung-Flynn, CM Brophy
Advanced Healthcare Materials
2016
Local delivery of PHD2 siRNA from ROS-degradable scaffolds to promote diabetic wound healing
JR Martin, CE Nelson, MK Gupta, F Yu, SM Sarett, KM Hocking, AC Pollins, LB Nanney, JM Davidson, SA Guelcher, CL Duvall
RSC Advances
2016
Oxidatively Degradable Poly(thioketal urethane)/Ceramic Composite Bone Cements with Bone-Like Strength
MA McEnery, S Lu, MK Gupta, KJ Zienkiewicz, JC Wenke, KN Kalpakci, D Shimko, CL Duvall, SA Guelcher
Frontiers in Bioengineering and Biotechnology
2016
Subfailure overstretch injury leads to reversible functional impairment and purinergic P2X7 receptor activation in intact vascular tissue
W Luo, CM Guth, O Jolayemi, CL Duvall, CM Brophy, J Cheung-Flynn
Advanced Materials
2016
Porous Silicon and Polymer Nanocomposites for Delivery of Peptide Nucleic Acids as anti-microRNA Therapies
KR Beavers, TA Werfel, T Shen, TE Kavanaugh, KV Kilchrist, JW Mares, JS Fain, CB Wiese, KC Vickers, SM Weiss, CL Duvall
Journal of Visualized Experiments
2016
Sustained Administration of β-cell Mitogens to Intact Mouse Islets Ex Vivo using Biodegradable Poly(Lactic-Co-Glycolic Acid) Microspheres
RC Pasek, TE Kavanaugh, CL Duvall, MA Gannon
Cellular and Molecular Bioengineering
2016
Mechanism of Enhanced Cellular Uptake and Cytosolic Retention of MK2 Inhibitory Peptide Nano-polyplexes
KV Kilchrist, BC Evans, CM Brophy, CL Duvall
Biomaterials
2016
Hydrophobic Interactions between Polymeric Carrier and Palmitic Acid-Conjugated siRNA Improve PEGylated Polyplex Stability and Enhance In Vivo Pharmacokinetics and Tumor Gene Silencing
SM Sarett, TA Werfel, I Chandra, MA Jackson, TE Kavanaugh, ME Hattaway, TD Giorgio, CL Duvall
Biomaterials
2016
Fluorocoxib A Loaded Nanoparticles Enable Targeted Visualization of Cyclooxygenase-2 in Inflammation and Cancer
MJ Uddin, TA Werfel, BC Crews, MK Gupta, TE Kavanaugh, PJ Kingsley, K Boyd, LJ Marnett, CL Duvall
