Publications

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ACS Nano
2019

Gal8 Visualization of Endosome Disruption Predicts Carrier-mediated Biologic Drug Intracellular Bioavailability

KV Kilchrist, SC Dimobi, MA Jackson, BC Evans, TA Werfel, EA Dailing, SK Bedingfield, IB Kelly, CL Duvall
AJP-Endocrinology and Metabolism
2019

Rapid changes in the microvascular circulation of skeletal muscle impair insulin delivery during sepsis

N Mignemi, P McClatchey, KV Kilchrist, I Williams, B Millis, K Syring, CL Duvall, D Wasserman, O McGuinness
Cellular and Molecular Bioengineering
2019

PLGA Microparticle Depots for Controlled and Sustained Release of Endosomolytic Nanoparticles

K Garland, S Sevimli, KV Kilchrist, CL Duvall, RS Cook, JT Wilson
European Journal of Pharmaceutical Science
2019

Preparation, preliminary pharmacokinetic and brain targeting study of metformin encapsulated W/O/W composite submicron emulsions promoted by borneol

L Hong, X Li, Y Bao, CL Duvall, C Zhang, W Chen, C Peng
Tissue Engineering B
2019

Applied Bioengineering in Tissue Reconstruction, Replacement, and Regeneration

JM Colazo, BC Evans, AF Farinas, S Al-Kassis, CL Duvall. WP Thayer
ACS Omega
2019

Optimizing Conjugation Efficiency and Residual Copper-Associated Toxicity in CuAAC-Functionalized Polyplexes for Delivery to Tumor-Associated Macrophages

EB Glass, S Masjedi, SO Dudzinski, AJ Wilson, CL Duvall, FE Yull, TD Giorgio
Journal of Controlled Release
2019

Systemic Delivery of a Gli Inhibitor via Polymeric Nanocarriers Blocks Tumor-Induced Bone Disease

JP Vanderburgh, KA Kwakwa, TA Werfel, AR Merkel, MK Gupta, RW Johnson, SA Guelcher, CL Duvall, JA Rhoades Sterling
Nature Communications
2019

Optimization of an Anionic, Endosome-Escaping Polymer to Potentiate Intracellular Delivery of Cationic Peptides, Biomacromolecules, and Nanoparticles

BC Evans, RB Fletcher, KV Kilchrist, EA Dailing, AJ Mukalel, JM Colazo, M Oliver, J Cheung-Flynn, CM Brophy, JW Tierney, JS Isenberg, KD Hankenson, K Ghimire, C Lander, CA Gersbach, CL Duvall
ACS Biomaterials Science & Engineering
2018

Drug Free ROS Sponge Polymeric Microspheres Reduce Tissue Damage from Ischemic and Mechanical Injury

KP O’Grady, TE Kavanaugh, H Cho, H Ye, MK Gupta, MC Madonna, J Lee, CM O’Brien, MC Skala, KA Hasty, CL Duvall
Cell Death and Disease
2018

Intrinsic Apoptotic Pathway Activation Increases Response to Anti-Estrogens in Luminal Breast Cancers

MM Williams, L Lee, TA Werfel, MM Joly, DJ Hicks, B Rahman, D Elion, C McKernan, V Sanchez, V Estrada, S Massarweh, R Elledge, CL Duvall, RS Cook
Journal of Biomedical Materials Research A
2018

Formulation and characterization of poly(propylacrylic acid)/poly(lactic-co-glycolic acid) blend microparticles for pH-dependent membrane disruption and cytosolic delivery

LP Fernando, JS Lewis, BC Evans, CL Duvall, BG Keselowsky
Cancer Research
2018

Selective mTORC2 inhibitor therapeutically blocks breast cancer cell growth and survival

TA Werfel, S Wang, MA Jackson, TE Kavanaugh, MM Joly, L Lee, DJ Hicks, VM Sanchez, PI Gonzalez-Ericsson, KV Kilchrist, SC Dimobi, SM Sarett, DM Brantley-Sieders , RS Cook, CL Duvall
Journal of Controlled Release
2018

Excipients for the Lyoprotection of MAPKAP Kinase 2 Inhibitory Peptide Nano-Polyplexes

AJ Mukalel, BC Evans, KV Kilchrist, EA Dailing, B Burdette, J Cheung-Flynn, CM Brophy, CL Duvall
Advanced Drug Delivery Reviews
2018

Harnessing Albumin as a Carrier for Cancer Therapies

EN Hoogenboezem, CL Duvall
Perfusion
2017

Unregulated saphenous vein graft distension decreases tissue viscoelasticity

ES Wise, KM Hocking, BC Evans, CL Duvall, J Cheung-Flynn, CM Brophy
Journal of Controlled Release
2017

Combinatorial Optimization of PEG Architecture and Hydrophobic Content Improves siRNA Polyplex Stability, Pharmacokinetics, and Potency In Vivo

TA Werfel, MA Jackson, TE Kavanaugh, KC Kirkbride, M Miteva, TD Giorgio, CL Duvall
ACS Nano
2017

Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol

MA Jackson, TA Werfel, E Curvino, F Yu, TE Kavanaugh, SM Sarett, M Dockery, KV Kilchrist, A Jackson, TD Giorgio, CL Duvall
Bioengineering & Translational Medicine
2017

Poly(2-propylacrylic acid) / poly(lactic-co-glycolic acid) blend microparticles as a targeted antigen delivery system to direct either CD4+ or CD8+ T cell activation

L Yang, E Bracho-Sanchez, MR Carstens, LP Fernando, JS Lewis, CL Duvall, BG Keselowsky
PNAS
2017

Lipophilic siRNA Targets Albumin in Situ and Promotes Bioavailability, Tumor Penetration, and Carrier-Free Gene Silencing

SM Sarett, TA Werfel, L Lee, MA Jackson, KV Kilchrist, DM Brantley-Sieders, CL Duvall
Tissue Engineering A
2017

ROS-shielding hydrogel for the delivery of adherent and non-adherent therapeutic cell types

BR Dollinger, MK Gupta, JR Martin, CL Duvall
Tissue Engineering Part C: Methods
2017

Porcine Ischemic Wound Healing Model for Preclinical Testing of Degradable Biomaterials

P Patil, JR Martin, SM Sarett, AC Pollins, NL Cardwell, JM Davidson, SA Guelcher, LB Nanney, CL Duvall
Advanced Functional Materials
2017

Thermogelling, ABC Triblock Copolymer Platform for Resorbable Hydrogels with Tunable, Degradation-Mediated Drug Release

MK Gupta, JR Martin, BR Dollinger, ME Hattaway, CL Duvall
Drug Delivery and Translational Research
2016

Particle-based Technologies for Osteoarthritis Detection and Therapy

TE Kavanaugh, TA Werfel, H Cho, KA Hasty, CL Duvall
Journal of Biomedical Materials Research A
2016

Hydrolytic Charge-reversal of PEGylated Polyplexes Enhances Intracellular Un-packaging and Activity of siRNA

TA Werfel, C Swain, CE Nelson, KV Kilchrist, BC Evans, M Miteva, CL Duvall
Journal of Colloid and Interface Science
2016

High conversion of HAuCl4 into gold nanorods: A re-seeding approach

SA Canonico-May, KR Beavers, MJ Melvin, AM Alkilany, CL Duvall, JW Stone