
ACS Nano
2019
Gal8 Visualization of Endosome Disruption Predicts Carrier-mediated Biologic Drug Intracellular Bioavailability
KV Kilchrist, SC Dimobi, MA Jackson, BC Evans, TA Werfel, EA Dailing, SK Bedingfield, IB Kelly, CL Duvall

AJP-Endocrinology and Metabolism
2019
Rapid changes in the microvascular circulation of skeletal muscle impair insulin delivery during sepsis
N Mignemi, P McClatchey, KV Kilchrist, I Williams, B Millis, K Syring, CL Duvall, D Wasserman, O McGuinness

Cellular and Molecular Bioengineering
2019
PLGA Microparticle Depots for Controlled and Sustained Release of Endosomolytic Nanoparticles
K Garland, S Sevimli, KV Kilchrist, CL Duvall, RS Cook, JT Wilson

European Journal of Pharmaceutical Science
2019
Preparation, preliminary pharmacokinetic and brain targeting study of metformin encapsulated W/O/W composite submicron emulsions promoted by borneol
L Hong, X Li, Y Bao, CL Duvall, C Zhang, W Chen, C Peng

Tissue Engineering B
2019
Applied Bioengineering in Tissue Reconstruction, Replacement, and Regeneration
JM Colazo, BC Evans, AF Farinas, S Al-Kassis, CL Duvall. WP Thayer

ACS Omega
2019
Optimizing Conjugation Efficiency and Residual Copper-Associated Toxicity in CuAAC-Functionalized Polyplexes for Delivery to Tumor-Associated Macrophages
EB Glass, S Masjedi, SO Dudzinski, AJ Wilson, CL Duvall, FE Yull, TD Giorgio

Journal of Controlled Release
2019
Systemic Delivery of a Gli Inhibitor via Polymeric Nanocarriers Blocks Tumor-Induced Bone Disease
JP Vanderburgh, KA Kwakwa, TA Werfel, AR Merkel, MK Gupta, RW Johnson, SA Guelcher, CL Duvall, JA Rhoades Sterling

Nature Communications
2019
Optimization of an Anionic, Endosome-Escaping Polymer to Potentiate Intracellular Delivery of Cationic Peptides, Biomacromolecules, and Nanoparticles
BC Evans, RB Fletcher, KV Kilchrist, EA Dailing, AJ Mukalel, JM Colazo, M Oliver, J Cheung-Flynn, CM Brophy, JW Tierney, JS Isenberg, KD Hankenson, K Ghimire, C Lander, CA Gersbach, CL Duvall

ACS Biomaterials Science & Engineering
2018
Drug Free ROS Sponge Polymeric Microspheres Reduce Tissue Damage from Ischemic and Mechanical Injury
KP O’Grady, TE Kavanaugh, H Cho, H Ye, MK Gupta, MC Madonna, J Lee, CM O’Brien, MC Skala, KA Hasty, CL Duvall

Cell Death and Disease
2018
Intrinsic Apoptotic Pathway Activation Increases Response to Anti-Estrogens in Luminal Breast Cancers
MM Williams, L Lee, TA Werfel, MM Joly, DJ Hicks, B Rahman, D Elion, C McKernan, V Sanchez, V Estrada, S Massarweh, R Elledge, CL Duvall, RS Cook

Journal of Biomedical Materials Research A
2018
Formulation and characterization of poly(propylacrylic acid)/poly(lactic-co-glycolic acid) blend microparticles for pH-dependent membrane disruption and cytosolic delivery
LP Fernando, JS Lewis, BC Evans, CL Duvall, BG Keselowsky

Cancer Research
2018
Selective mTORC2 inhibitor therapeutically blocks breast cancer cell growth and survival
TA Werfel, S Wang, MA Jackson, TE Kavanaugh, MM Joly, L Lee, DJ Hicks, VM Sanchez, PI Gonzalez-Ericsson, KV Kilchrist, SC Dimobi, SM Sarett, DM Brantley-Sieders , RS Cook, CL Duvall

Journal of Controlled Release
2018
Excipients for the Lyoprotection of MAPKAP Kinase 2 Inhibitory Peptide Nano-Polyplexes
AJ Mukalel, BC Evans, KV Kilchrist, EA Dailing, B Burdette, J Cheung-Flynn, CM Brophy, CL Duvall

Advanced Drug Delivery Reviews
2018
Harnessing Albumin as a Carrier for Cancer Therapies
EN Hoogenboezem, CL Duvall

Perfusion
2017
Unregulated saphenous vein graft distension decreases tissue viscoelasticity
ES Wise, KM Hocking, BC Evans, CL Duvall, J Cheung-Flynn, CM Brophy

Journal of Controlled Release
2017
Combinatorial Optimization of PEG Architecture and Hydrophobic Content Improves siRNA Polyplex Stability, Pharmacokinetics, and Potency In Vivo
TA Werfel, MA Jackson, TE Kavanaugh, KC Kirkbride, M Miteva, TD Giorgio, CL Duvall

ACS Nano
2017
Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol
MA Jackson, TA Werfel, E Curvino, F Yu, TE Kavanaugh, SM Sarett, M Dockery, KV Kilchrist, A Jackson, TD Giorgio, CL Duvall

Bioengineering & Translational Medicine
2017
Poly(2-propylacrylic acid) / poly(lactic-co-glycolic acid) blend microparticles as a targeted antigen delivery system to direct either CD4+ or CD8+ T cell activation
L Yang, E Bracho-Sanchez, MR Carstens, LP Fernando, JS Lewis, CL Duvall, BG Keselowsky

PNAS
2017
Lipophilic siRNA Targets Albumin in Situ and Promotes Bioavailability, Tumor Penetration, and Carrier-Free Gene Silencing
SM Sarett, TA Werfel, L Lee, MA Jackson, KV Kilchrist, DM Brantley-Sieders, CL Duvall

Tissue Engineering A
2017
ROS-shielding hydrogel for the delivery of adherent and non-adherent therapeutic cell types
BR Dollinger, MK Gupta, JR Martin, CL Duvall

Tissue Engineering Part C: Methods
2017
Porcine Ischemic Wound Healing Model for Preclinical Testing of Degradable Biomaterials
P Patil, JR Martin, SM Sarett, AC Pollins, NL Cardwell, JM Davidson, SA Guelcher, LB Nanney, CL Duvall

Advanced Functional Materials
2017
Thermogelling, ABC Triblock Copolymer Platform for Resorbable Hydrogels with Tunable, Degradation-Mediated Drug Release
MK Gupta, JR Martin, BR Dollinger, ME Hattaway, CL Duvall

Drug Delivery and Translational Research
2016
Particle-based Technologies for Osteoarthritis Detection and Therapy
TE Kavanaugh, TA Werfel, H Cho, KA Hasty, CL Duvall

Journal of Biomedical Materials Research A
2016
Hydrolytic Charge-reversal of PEGylated Polyplexes Enhances Intracellular Un-packaging and Activity of siRNA
TA Werfel, C Swain, CE Nelson, KV Kilchrist, BC Evans, M Miteva, CL Duvall

Journal of Colloid and Interface Science
2016
High conversion of HAuCl4 into gold nanorods: A re-seeding approach
SA Canonico-May, KR Beavers, MJ Melvin, AM Alkilany, CL Duvall, JW Stone